Multiple sclerosis remains a mysterious condition, as its origin is not clear, yet it leads to a relatively slower or quicker persistent disability. Advances in MS treatment are still very limited.
It is very difficult to achieve the regeneration of the damaged myelin cells - motor and sensitive disorders - if patients have had them for more than a year old.
The main direction of neurorehabilitation in the whole world is the symptomatic therapy and rest, short courses of immunosuppressive hormonal or cytostatic therapies.
A chemotherapy drug Cladribine, previously used to treat one of the forms of leukemia, a blood tumor, has recently been presented.
The interferon group drugs prolong remissions and extend the time before patients become disabled (effective up to 30%).
Multiple sclerosis is a psychosomatic illnesses.
We have a different, more optimistic view on the problem of MS, since we adhere to the hypothesis, that the primacy of the incorrect psychological attitudes of a person, leads to a chronic stress reaction and eventually originating the disease.
Starting from functional motor and sensitive disorders, it eventually leads to organic brain lesions in the form of demyelination.
It is common that at the beginning of this process, acute stress (both psychological and physical) is detected. Stresses are a normal phenomenon of human life, but not everyone can respond to stress adequately.
Some people are taught by parents and society to keep all emotions to themselves. For years, they have anxious and strained attitudes towards everything unfamiliar, these people are afraid to be condemned by the public for completely innocent acts.
As a result, all these "junk files" (concealed emotions, fears, self-torture, condemnation of others, rigidity in judgments) are infiltrated into the "operating system" of a human leading to persistent muscular tension - muscle carapace (according to V. Raikh) and a lot of vegetative disorders.
A well-known fact about South-Eastern Asian countries, where the population is very high and the MS rate is low, supports this hypothesis.
This is not due to their climate or nutrition, but owing to the characteristic religious attitude to the world.
"The reincarnation chain of a soul is infinite, what I will not do in this life - I will in the next one. Material values are just an illusion, they are not worthy, but the positive experience in this life is. One should not hurt a living being, as it will badly effect one`s karma."
If you have ever been to these countries, then you could not help noticing those smiles and benignity in the atmosphere of mutual benevolence, which is everywhere. You won`t see a mother screaming at her child.
As a doctor, I was highly interested in people`s muscular tension, and specifically asked various inhabitants of Phuket island to allow me to touch their shoulder girdle, and have to admit, there was rarely any tension.
Meanwhile in the so-called “civilized” developed European countries it is always the opposite. In terms of body psychotherapy, the shoulder girdle tension reflects the psychological state of a person, as the saying goes, “Carrying the weight of the world on one`s shoulders.”
After all, this is the consequence of the mass media influence, the upbringing aimed at compulsory success, the fear of losing what you have gained.
Thus, the psychosomatic component in the MS development takes quite a rightful place. On the bright side, psychosomatic disorders are effectively treated, not just with various medications, but with relentless inner psychological work leading to spiritual growth.
Naturally, during the initial stages, the help of a professionally qualified psychologist and psychotherapist are required.
How to cure multiple sclerosis? Stem cell therapy treatment.
This treatment relies on strengthening the regenerative capabilities of the diseased by injecting stem cells. In terms of MS, one of the effects is the activation of myelin-producing Schwann cells and the optimization of neuropeptide and trophic regulation in the central nervous system.
The second important effect is an immunomodulatory effect of the mesenchymal stem cells transplantation, when excessively activated lymphocytic clones detain their activity against their own myelin. In immunology, this process is connected with the pronounced inhibition of antigen-presenting function of dendritic cells.
The third important mechanism is the neurogenesis in the neural stem cells localization zones.
As a therapy result, the neuromuscular conduction is quickly restored, paralyzed limbs begin to move again. Naturally, this process is not immediate - the approximate time for restoration of myelin and the formation of new neural ensembles takes about 6 months. It is optimal to have a second cell injection 2-3 months after the first transplantation, as it comes to treating MS.
In our experience, the use of mesenchymal cells for MS treatment results in the following positive phenomena observed: the increase in the daily activity time, better tolerance of physical exercises, retrobulbar neuritis regression, the improvement or complete normalization of the pelvic organs functioning, the decrease of sensitive disorders. The EDSS scale is usually reduced by 2-3 points.
Three-quarters of patients observed within at least 5 years do not have disease progression after the therapy. It is very important to go through the stem cell treatment while a person can still walk.
We have observed the cases when MS patients with a higher degree of demyelination had better results in motor rehabilitation than patients with a small number of lesions. From the neurophysiological point of view, this fact is explained by the ability of neurons to build new functional connections to provide either function, i.e. the plasticity of the central nervous system.
The following cellular products for MS therapy are currently used in the world:
1) autologous mesenchymal cells from adipose tissue of the patient;
2) autologous hematopoietic stem cells transplanted after carrying out the protocol of myeloablation (chemotherapeutic inhibition of bone marrow hematopoiesis);
3) autologous mesenchymal stem cells of the patient's bone marrow;
4) umbilical blood compatible in group and Rh;
5) mesenchymal stem cells from umbilical cord (varton jelly) and placenta.
We use the last of the listed cell products, viewing it as the most effective and safe, proven in the long-term practice of MS cell treatment. Donor cells do not remain in the patient's body forever, as only 2 months after the transplantation the immune system eliminates them. The therapeutic effect lies in suppressing the autoimmune reactions and stimulating patient's own neurogenesis.
There is no proof of that mesenchymal donor stem cells can cause tumor development; neither theoretically, nor practically any correlation with cancer development after stem cell transplantation was found.
It is worth mentioning, that MS patients have no cancer at all - apparently, this is a feature of the overly strained cellular immunity.
MS treatment reviews
One of the cases of lost functions restoration: patient Sh., 53 years, has suffered from multiple sclerosis for 8 years. In 2005 she has lost the ability to move without help, and has been limited to a wheelchair. At the time of admission to the rehabilitation department 13.03.06 she had fatigue, the image in her eyes was constantly "jumping," legs anesthesia to the upper third of the thighs, a pronounced spasticity in all groups of hip muscles, especially those leading to impaired pelvic organs. NMRT showed multiple demyelination around the corpus callosum and multiple periventricular lesions.
Together with pulse therapy (dexamethasone and cyclosporin-A), human stromal cells were injected endolumbally at a dose of 5 million cells, volume of 2 mil. The meningism period of moderate severity lasted 4 days. On the 10th day after the transplantation, the patient developed a superficial sensation in her legs, there was a lack of proprioception, the spasticity has decreased (the patient began to move legs and feet), vision became clearer, urination control was established. When examined after 6 months: walks with a stick, no sensitive disorders, no pelvic disorders, retrobulbar neuritis regressed. Patient spent her summer quite actively, did small work in the garden. Disturbing pain syndrome due to the long-standing arthrosis of both knee joints.
Another patient Zinkin Vyacheslav Anatolyevich born in 1976 from Kazakhstan tells visitors about the results of his treatment in our clinic.
Initial condition: walked with a stick, accompanied for a distance of 200 m. Now he walks without any help, movement unlimited, though periodic medical support is required.
Our team was very pleased to see Vyacheslav in October 2009, arriving for a second transplantation of SC: first of all, he came all by himself, driving from Uralsk (Kazakhstan) to our clinic, neurologically weak only in Babinskiy symptom on the right, and second of all – got rid of 18 kg of excessive weight, looked way younger. He told us how the neurologists who monitored him were confused with the fact that "the illness is going in the wrong direction."
Another patient coming from Noymarkt, Germany is Dmitry, 24 years old (treated in August 2009) - can share his impressions and tell about his current condition after 16:00 Germany time.
Lisa Marochkina is now a 3rd year student of the medical academy: “In 2009 I could not walk by myself (I could walk 50 meters with my mother supporting me) and I had a very indistinct speech.”
Recently, patients who have entered remission with a significant neurological improvement are asked to give their phone numbers for internet publications, guided by the principle: recover yourself, help others. We are pleased to place their numbers.
Luba 26 years old (Samara region) - Arrived with a scotoma (field of vision loss). Gained her vision back, the effect is persistent. Currently works as a translator on her computer.
Katya 28 years old (Izhevsk) - The initial condition: cannot move, persistent spasticity in her legs with the occurrence of pressure ulcers in popliteal areas. Traditional neurologists giving up on treating her. “In 3 years I was able to stand up, move around the house.”
Sasha (Magnitogorsk) – Has worked as a teacher for more than 4 years, fully active. In 2007 she came with her mother supporting her by hand, as she could not walk more than 30 m without help. Currently, as the place of residence neurologist prescribed, receives copaxone.
Andrei (Uzlovaya, Tula region) - Arrived 2 years ago in a very bad condition, transported only in a wheelchair. Now he moves around the house with a walker
Eugene (Yaroslavl) – Arrived in 2010 supported by the hand; complete blindness due to the optic nerves atrophy, most likely due to demyelinating processes. The Israeli center of neurology therapy did not work for him. Now he independently walks around the city, uses public transport is able to watch TV. There is still minor color perception problem and central scotoma of both eyes - however, the process of regeneration continues and the young man sees everything better and better. He is under the observation of ophthalmologists and neurologists of the Yaroslavl Medical Academy.
Olga (Nizhny Novgorod) is another case of recovering from MS (March 2011). During the 10 days of therapy, the EDSS scale went from 5 points to 3.5 points. “I am very happy to have the opportunity to freely move, planning to start wearing heels again! (Disheartened by my illness, I gave away my model shoes to my girlfriends)”
The list is far from complete.
I also recommend discussing psychological problems with our psychologist Timur Khabirov.
Tags: MS treatment, multiple sclerosis, center of multiple sclerosis, MS causes, multiple sclerosis can be cured.